USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P55957 USC-OGP 2-DE database:  P55957 P55957 General information about the entry View entry in simple text format Entry name BID_HUMAN Primary accession number P55957 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=BH3-interacting domain death agonist; AltName: Full=p22 BID; Short=BID; Contains: RecName: Full=BH3-interacting domain death agonist p15; AltName: Full=p15 BID; Contains: RecName: Full=BH3-interacting domain death agonist p13; AltName: Full=p13 BID; Contains: RecName: Full=BH3-interacting domain death agonist p11; AltName: Full=p11 BID;. Gene name Name=BID Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0223: pI=4.97; Mw=20501 Cross-references UniProtKB/Swiss-Prot P55957; BID_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name BID_HUMAN Primary accession number P55957 Secondary accession number(s) Q549M7 Q71T04 Q7Z4M9 Q8IY86 Sequence was last modified on  November 1, 1997 (version 1) Annotations were last modified on  March 15, 2017 (version 173) Name and origin of the protein Description RecName: Full=BH3-interacting domain death agonist; AltName: Full=p22 BID; Short=BID; Contains: RecName: Full=BH3-interacting domain death agonist p15; AltName: Full=p15 BID; Contains: RecName: Full=BH3-interacting domain death agonist p13; AltName: Full=p13 BID; Contains: RecName: Full=BH3-interacting domain death agonist p11; AltName: Full=p11 BID; Gene name Name=BID Encoded on Name=BID Keywords 3D-structure; Acetylation; Alternative splicing; Apoptosis; Complete proteome; Cytoplasm; Membrane; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF042083; AAC34365.1; -; mRNA EMBL AF250233; AAO32633.1; -; mRNA EMBL AY005151; AAF89091.1; -; mRNA EMBL AF087891; AAP97190.1; -; mRNA EMBL CR456389; CAG30275.1; -; mRNA EMBL CR407603; CAG28531.1; -; mRNA EMBL AY309922; AAP50259.1; -; Genomic_DNA EMBL BC009197; AAH09197.1; -; mRNA EMBL BC022072; AAH22072.2; ALT_INIT; mRNA EMBL BC033634; AAH33634.1; -; mRNA EMBL BC036364; AAH36364.2; -; mRNA CCDS CCDS13747.1; -. [P55957-2]; . CCDS CCDS13748.1; -. [P55957-1]; . CCDS CCDS13749.1; -. [P55957-4]; . RefSeq NP_001187.1; NM_001196.3. [P55957-1]; . RefSeq NP_001231496.1; NM_001244567.1. [P55957-1]; . RefSeq NP_001231498.1; NM_001244569.1. [P55957-4]; . RefSeq NP_001231499.1; NM_001244570.1. [P55957-4]; . RefSeq NP_001231501.1; NM_001244572.1. [P55957-4]; . RefSeq NP_932070.1; NM_197966.2. [P55957-2]; . RefSeq NP_932071.1; NM_197967.2. [P55957-4]; . UniGene Hs.517145; -; . UniGene Hs.591054; -; . PDB 1ZY3; NMR; -; B=82-101 PDB 2BID; NMR; -; A=1-195 PDB 2KBW; NMR; -; B=76-106 PDB 2M5B; NMR; -; B=80-101 PDB 2M5I; NMR; -; A=61-195 PDB 4BD2; X-ray; 2.21 A; C=76-109 PDB 4QVE; X-ray; 2.05 A; B=76-109 PDB 4ZEQ; X-ray; 1.80 A; B=79-104 PDB 4ZIG; X-ray; 2.20 A; B=79-98 PDB 4ZII; X-ray; 2.19 A; C=76-109 PDB 5AJJ; X-ray; 1.75 A; B=79-112 PDB 5C3F; X-ray; 1.43 A; B=80-101 PDBsum 1ZY3; -; . PDBsum 2BID; -; . PDBsum 2KBW; -; . PDBsum 2M5B; -; . PDBsum 2M5I; -; . PDBsum 4BD2; -; . PDBsum 4QVE; -; . PDBsum 4ZEQ; -; . PDBsum 4ZIG; -; . PDBsum 4ZII; -; . PDBsum 5AJJ; -; . PDBsum 5C3F; -; . ProteinModelPortal P55957; -; . SMR P55957; -; . BioGrid 107106; 53; . DIP DIP-34937N; -; . IntAct P55957; 35; . MINT MINT-270277; -; . STRING 9606.ENSP00000318822; -; . iPTMnet P55957; -; . PhosphoSitePlus P55957; -; . BioMuta BID; -; . DMDM 2493285; -; . OGP P55957; -; . EPD P55957; -; . MaxQB P55957; -; . PaxDb P55957; -; . PeptideAtlas P55957; -; . PRIDE P55957; -; . TopDownProteomics P55957-1; -. [P55957-1]; . TopDownProteomics P55957-4; -. [P55957-4]; . DNASU 637; -; . Ensembl ENST00000317361; ENSP00000318822; ENSG00000015475. [P55957-2]; . Ensembl ENST00000342111; ENSP00000344594; ENSG00000015475. [P55957-3]; . Ensembl ENST00000399765; ENSP00000382667; ENSG00000015475. [P55957-4]; . Ensembl ENST00000399767; ENSP00000382669; ENSG00000015475. [P55957-4]; . Ensembl ENST00000399774; ENSP00000382674; ENSG00000015475. [P55957-1]; . Ensembl ENST00000551952; ENSP00000449236; ENSG00000015475. [P55957-1]; . Ensembl ENST00000611040; ENSP00000483709; ENSG00000015475. [P55957-4]; . Ensembl ENST00000614949; ENSP00000477773; ENSG00000015475. [P55957-4]; . Ensembl ENST00000615414; ENSP00000483534; ENSG00000015475. [P55957-4]; . Ensembl ENST00000622694; ENSP00000480414; ENSG00000015475. [P55957-1]; . GeneID 637; -; . KEGG hsa:637; -; . UCSC uc002znc.3; human. [P55957-1]; . CTD 637; -; . DisGeNET 637; -; . GeneCards BID; -; . HGNC HGNC:1050; BID; . HPA CAB003771; -; . HPA HPA000722; -; . MIM 601997; gene; . neXtProt NX_P55957; -; . OpenTargets ENSG00000015475; -; . PharmGKB PA25353; -; . eggNOG ENOG410IVZ7; Eukaryota; . eggNOG ENOG410ZF8F; LUCA; . GeneTree ENSGT00390000002868; -; . HOGENOM HOG000010016; -; . HOVERGEN HBG001703; -; . InParanoid P55957; -; . KO K04726; -; . OMA RDVFRTT; -; . OrthoDB EOG091G0LRX; -; . PhylomeDB P55957; -; . TreeFam TF102047; -; . Reactome R-HSA-111447; Activation of BAD and translocation to mitochondria; . Reactome R-HSA-111452; Activation and oligomerization of BAK protein; . Reactome R-HSA-111453; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members; . Reactome R-HSA-114294; Activation; translocation and oligomerization of BAX; . Reactome R-HSA-6803204; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; . Reactome R-HSA-75108; Activation; myristolyation of BID and translocation to mitochondria; . SIGNOR P55957; -; . ChiTaRS BID; human; . EvolutionaryTrace P55957; -; . GeneWiki BH3_interacting-domain_death_agonist; -; . GeneWiki BH3_interacting_domain_death_agonist; -; . GenomeRNAi 637; -; . PMAP-CutDB P55957; -; . PRO PR:P55957; -; . Proteomes UP000005640; Chromosome 22; . Bgee ENSG00000015475; -; . CleanEx HS_BID; -; . ExpressionAtlas P55957; baseline and differential; . Genevisible P55957; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0032592; C:integral component of mitochondrial membrane; IEA:Ensembl; . GO GO:0016020; C:membrane; TAS:ProtInc; . GO GO:0005741; C:mitochondrial outer membrane; TAS:Reactome; . GO GO:0005739; C:mitochondrion; TAS:ProtInc; . GO GO:0005123; F:death receptor binding; TAS:ProtInc; . GO GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl; . GO GO:0008637; P:apoptotic mitochondrial changes; TAS:ProtInc; . GO GO:0007420; P:brain development; IEA:Ensembl; . GO GO:0090150; P:establishment of protein localization to membrane; IDA:BHF-UCL; . GO GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc; . GO GO:0034349; P:glial cell apoptotic process; IEA:Ensembl; . GO GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl; . GO GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IEA:Ensembl; . GO GO:0097345; P:mitochondrial outer membrane permeabilization; IEA:Ensembl; . GO GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl; . GO GO:0051402; P:neuron apoptotic process; TAS:HGNC; . GO GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB; . GO GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB; . GO GO:2000271; P:positive regulation of fibroblast apoptotic process; IEA:Ensembl; . GO GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome; . GO GO:0010918; P:positive regulation of mitochondrial membrane potential; IEA:Ensembl; . GO GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0032464; P:positive regulation of protein homooligomerization; IDA:BHF-UCL; . GO GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB; . GO GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB; . GO GO:0051260; P:protein homooligomerization; IEA:Ensembl; . GO GO:0006626; P:protein targeting to mitochondrion; IEA:Ensembl; . GO GO:0042981; P:regulation of apoptotic process; TAS:Reactome; . GO GO:0042127; P:regulation of cell proliferation; IEA:Ensembl; . GO GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl; . GO GO:0001836; P:release of cytochrome c from mitochondria; IDA:HGNC; . GO GO:0032355; P:response to estradiol; IEA:Ensembl; . GO GO:0042770; P:signal transduction in response to DNA damage; TAS:UniProtKB; . InterPro IPR020728; Bcl2_BH3_motif_CS; . InterPro IPR010479; BID; . PANTHER PTHR35447; PTHR35447; 1; . Pfam PF06393; BID; 1; . PIRSF PIRSF038018; BID; 1; . PROSITE PS01259; BH3; 1; .

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